Evidence from multiple contexts suggests that the Graduation Approach, which provides holistic livelihood support for ultra-poor households, has lasting positive impacts on a range of outcomes. However, Graduation programs are relatively expensive because of the intense level of support they offer. The costs pose a challenge for governments that want to implement the approach at scale. In Uganda, researchers worked with Innovations for Poverty Action to conduct a randomized evaluation to better understand the effectiveness of several variants of a Graduation program focused on improving nutrition and self-reliance among populations in and around a refugee settlement. The program had significant positive impacts for both program participants and their households on key outcomes, including food security, nutrition, and self-reliance. All variations of the program also had large positive returns on investment.